SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients aged 12 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO.
If you don't know your mutation, talk to your healthcare provider to learn if you have an indicated CF gene mutation.
It is not known if SYMDEKO is safe and effective in children under 12 years of age.
F508del/F508del or
c.1521_1523delCTT |
|||||||
---|---|---|---|---|---|---|---|
At least one other responsive mutation from the following list: | |||||||
711+3A→G
c.579+3A>G |
A455E
c.1364C>A |
D579G
c.1736A>G |
E193K
c.577G>A |
K1060T
c.3179A>C |
R117C
c.349C>T |
S945L
c.2834C>T |
|
2789+5G→A
c.2657+5G>A |
A1067T
c.3199G>A |
D1152H
c.3454G>C |
E831X
c.2491G>T |
L206W
c.617T>G |
R347H
c.1040G>A |
S977F
c.2930C>T |
|
3272-26A→G
c.3140-26A>G |
D110E
c.330C>A |
D1270N
c.3808G>A |
F1052V
c.3154T>G |
P67L
c.200C>T |
R352Q
c.1055G>A |
||
3849+10kbC→T
c.3718-2477C>T |
D110H
c.328G>C |
E56K
c.166G>A |
F1074L
c.3222T>A |
R74W
c.220C>T |
R1070W
c.3208C>T |
If you don't know your mutation, talk to your healthcare provider to learn if you have an indicated CF gene mutation.
It is not known if SYMDEKO is safe and effective in children under 12 years of age.
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Talk to your doctor before taking SYMDEKO if you take any of the medicines or herbal supplements listed above.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, because the dose of SYMDEKO may need to be adjusted when taken with certain medicines.
Your doctor may do blood tests to check the liver more often if you have had high liver enzymes in your blood in the past.
The most common side effects of SYMDEKO include headache, nausea, sinus congestion, and dizziness.
These are not all the possible side effects of SYMDEKO. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including Patient Information.
SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients aged 12 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO.
Talk to your doctor to learn if you have an indicated CF gene mutation.
It is not known if SYMDEKO is safe and effective in children under 12 years of age.
SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients aged 12 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO.
Talk to your doctor to learn if you have an indicated CF gene mutation.
It is not known if SYMDEKO is safe and effective in children under 12 years of age.